324 Tetracycline-Oral
NADA No.: 065-496

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Active Ingredients:

Each pound contains 324 g of tetracycline hydrochloride.

Indications:

For use in the control and treatment of the following conditions in swine, calves and poultry.

Swine:

Bacterial enteritis (scours) caused by Escherichia coli and bacterial pneumonia associated with Pasteurella spp., Hemophilus spp. and Klebsiella spp. susceptible to tetracycline.

Calves:

Bacterial enteritis (scours) caused by Escherichia coli and bacterial pneumonia (shipping fever complex) associated with Pasteurella spp., Hemophilus spp., and Klebsiella spp. susceptible to tetracycline.

Chickens:


Control of chronic respiratory disease (CRD) and air sac infection caused by Mycoplasma gallisepticum and Escherichia coli; infectious synovitis caused by Mycoplasma synoviae susceptible to tetracycline.

Turkeys:

Control of infectious synovitis caused by Mycoplasma synoviae and bluecomb (transmissible enteritis, coronaviral enteritis) caused by complicating bacterial organisms susceptible to tetracycline.

Dosage and Administration:

Administer TETRACYCLINE HYDROCHLORIDE SOLUBLE POWDER-324 in the drinking water of swine and calves at a drug level of tetracycline hydrochloride per gallon to provide approximately 10 mg/lb. of body weight per day, for three (3) to five (5) days. Administer TETRACYCLINE HYDROCHLORIDE SOLUBLE POWDER-324 in the drinking water of chickens and turkeys at a level of 25 mg/lb. of body weight per day, for 7-14 days. Do not mix the product with milk or milk replacers. Administer one (1) hour before or two (2) hours after feeding milk or milk replacers. The drug use level must be adjusted to provide 10 mg/lb. of body weight per day in divided doses for swine and calves or, in the case of chickens and turkeys, 25 mg/lb.

Mixing Instructions:

The enclosed blue cup, when level full, provides approximately 71.4 g (2.52 oz.) of finished product which contains 51.0 g of tetracycline hydrochloride.

Swine:

A stock solution of 71.4 g dissolved in 1,500 mL (approximately 50 fl. oz. or 3 pints) of warm water provides about 34 mg of tetracycline hydrochloride activity per mL. The stock solution metered at 1 oz./gallon will provide drinking water which contains approximately 1,000 mg of tetracycline hydrochloride activity per gallon.

Calves:

For individual dosing, prepare a solution of 71.4 g dissolved in 500 mL (approximately 16 fl. oz. or 1 pint) of warm water which provides about 100 mg of tetracycline hydrochloride activity per mL. Administer 5 mL (1 measuring teaspoonful) of the stock solution (100 mg/mL) twice a day for each 100 lbs. of body weight as a drench or by a dose syringe. This will provide the recommended dosage level of 10 mg/lb. of body weight per day in divided doses.

Chickens and Turkeys:


A stock solution of 71.4 g dissolved in 1,500 mL (approximately
50 fl. oz. or 3 pints) of warm water provides about 34 mg of tetracycline hydrochloride activity
per mL. The stock solution metered at 1 oz./gallon will provide drinking water which contains approximately 1,000 mg of tetracycline hydrochloride activity per gallon.

Note:

The concentration of the drug required in medicated water must be adequate to compensate for variation in the age of the animals, feed consumption and the environmental temperature and humidity, each of which affects water consumption. The contents of the container (2 lb.) will provide sufficient drug to treat 64,800 total pounds of swine or calves for a single day at the recommended dosage level of 10 mg/lb. of body weight in divided doses. The same container will treat 25,920 lbs. of poultry when supplied at 25 mg/lb.

Cautions:

Use as the sole source of tetracycline. Not to be used in swine or calves for more than five days. Not to be used in chickens or turkeys for more than 14 consecutive days. When used in plastic or stainless steel waterers or automatic medicators, prepare a fresh solution every 24 hours. When used in galvanized waterers, prepare a fresh solution every 12 hours. If the condition does not improve within two to three days, consult a veterinarian.

FOR USE IN ANIMALS ONLY.
KEEP OUT OF REACH OF CHILDREN.

Warnings:

Do not slaughter swine for food purposes within four (4) days of treatment. Do not slaughter cattle for food purposes within five (5) days of treatment. Do not slaughter poultry for food within four (4) days of treatment. Not for use in poultry producing eggs for human consumption.

Presentation:

5 lb containers.

VEDCO - 11/10/98.1